Although it has been discovered that obesity plays a role in the onset of type 2 diabetes, scientists aren't certain how the excess weight triggers the disease.

What scientists do know is that obesity causes stress in the endoplasmic reticulum (ER), a system of cell membranes found inside cells. This stress results in the suppression of the signals of insulin receptors, leading to insulin resistance. Insulin is a hormone that converts blood sugar to energy.

The ER has been compared to a synthetic machine of a cell, responsible for processing proteins and fats. Scientists have also referred to the ER as a factory for producing protein, as well as the site where excess blood fats are processed.

When the body is bombarded with nutrients the following occurs:

1. Nutrients must be processed, stored and utilized
2. The ER factory becomes overworked and starts sending SOS signals
3. SOS signals tell the cells to dampen their insulin receptors
4. The ER restrains normal responses to insulin
5. Insulin can no longer clear sugar from the body

Studies have revealed that if people can find a way to reduce ER stress, generate less ER stress or find a way for the body to handle stress more efficiently, type 2 diabetes might be easier to manage.

Reversing Diabetes

Adult onset, Type 2 diabetes is the most common form of diabetes affecting over 15 million Americans who are walking down a seemingly inevitable road to disability and early death. Ahead of them lie blindness, painful neuropathy, and frequent infections.One hundred and fifty diabetic legs are amputated every day in this country and another 70 diabetics start on dialysis for the first time every day. At any turn in the road a stroke or heart attack may strike them with paralysis or death.It is a road dark with shadows that the diabetic sees stretched out before him or her.

The good news is that some diabetes can be reversed. It is not always inevitable that one must walk down this road of pain and misery. With some people diet, weight loss and fasting can reverse diabetes and help them to do an about face and literally walk away from all of these terrible complications.

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